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sitagliptin add-on therapy in patients with type 2 diabetes inadequately controlled on the combination of metformin immediate-release and glimepiride.

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the usual recommended dose of glucovance for a patient who has not benefitted from the use of either metformin or glibenclamide is one glucovance 500 2.

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additional findings included elevated blood lactate concentrations 5 mmol l , anion gap acidosis without evidence of ketonuria or ketonemia , and an increased lactate pyruvate ratio; metformin plasma levels generally 5 mcg ml.

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